As we transition into older age, our bodies undergo gradual yet significant physiological changes. Reduced Nitric Oxide (NO) production is one such characteristic alteration, contributing to age-related health concerns.

NO, a gas endogenously produced by our bodies, plays a crucial role in numerous physiological processes. Its primary function lies in vasodilation, enhancing blood flow and oxygen delivery to tissues. Additionally, NO exerts anti-inflammatory, immune-modulatory, and neuroprotective effects, contributing to overall health and well-being.

However, nitric oxide production steadily declines after our 40s, decreasing by approximately 10% per decade. This decline is associated with various age-related conditions, including cardiovascular disease, cognitive decline, and chronic pain. Reduced blood flow due to insufficient NO contributes to tissue hypoxia, impaired cellular function, and inflammation, ultimately impacting organ health and well-being.

Fortunately, various strategies can support optimal NO levels. Lifestyle modifications such as regular exercise, a balanced diet rich in fruits and vegetables (particularly dark leafy greens like spinach and kale), and adequate sleep have demonstrated efficacy in boosting NO production. Additionally, targeted dietary supplements containing L-citrulline or beetroot extract, precursors to NO synthesis, are gaining traction as potential interventions.

N1O1 and Berkeley Life (use code CPUC1) are two brands offering NO-supporting supplements available at Thryv Medical. N1O1 utilizes a proprietary blend of L-citrulline and beetroot extract as a dissolvable tablet, delivering readily available NO through the oral microbiome and thereby bypassing conversion steps. Conversely, Berkeley Life provides pure L-citrulline malate as capsules, empowering the body to naturally synthesize NO in the stomach. Both approaches, backed by clinical research, hold promise for individuals seeking to optimize NO levels.

Interestingly enough, it has been found that regularly using mouthwash or antiacids can inhibit NO production within the body, essentially nullifying the benefits of the molecule.

Beyond the physical benefits, studies suggest NO exerts significant neuroprotective effects. Its involvement in memory enhancement and potential protection against neurodegenerative diseases like Alzheimer's highlights its crucial role in cognitive health during aging. Furthermore, NO's anti-inflammatory properties offer potential relief from chronic pain and joint issues, further improving the quality of life in older adults.

NO emerges as a key molecule for maintaining healthy aging. Its multifaceted roles in cardiovascular, cognitive, and immune functions underscore its importance in promoting well-being. While age-related decline is inevitable, lifestyle modifications and targeted interventions like NO-supporting supplements can help optimize NO levels and potentially mitigate the detrimental effects of age-associated health concerns.

Sources: n1o1.com, berkeleylife.com

Disclaimer These statements have not been evaluated by the FDA. Any supplement is not intended to diagnose, treat, cure, or prevent any disease.